The Fox Lab pursues structural and functional studies of eukaryotic chromosomes and associated regulatory proteins using the budding yeast Saccharomyces cerevisiae as a model organism.

Major Interests Include:

-DNA replication origins: selection and function within chromatin

-The origin recognition complex (ORC)

-Heterochromatin (silencing) and Silent Information Regulator (SIR) proteins

-Cell cycle regulators and chromatin dynamics