Lawrence Kahan
 |
Professor
Office: (608) 263-1864 |
Education
- B.A., 1965, University of California, Berkeley;
- Ph.D., 1971, Brandeis University;
- Postdoctoral, 1970-73, University of Wisconsin (M. Nomura).
Honors & Awards
- Inbusch Award, 1976;
- H.I. Romnes Faculty Fellowship, 1979.
Research Interests
Work in our laboratory is directed toward elucidating molecular mechanisms involved in the control of embryonic cell migration. We study the migration of both malignant (embryonal carcinoma) and nonmalignant (ES) cells in response to an as yet uncharacterized form of renin. We are proceeding to isolate and and characterize the specific form of renin which stimulates migration. We then plan to characterize the receptor for this stimulatory factor, determine the relationship of that receptor to embryonic development and identify other ligands that interact with the receptor during development.
Publications of Note
Syu, W.-J. and Kahan, L. 1992. Both Ends of Escherichia coli Ribosomal
Protein S13 are Immunochemically Accessible in situ. J. Protein
Chemistry 11: 225-230.
Scheinman, A., Atha, T., Aguinaldo, A.M., Kahan, L., Shankweiler, G.
and Lake, J.A. 1992. Mapping the Three-dimensional Locations of
Ribosomal RNA and Proteins. Biochimie 74: 307-317.
Ho, H.-N. H., Kallstrom, G., Trotta, C., Lund, E., Kahan, L., Hedges,
J., Dahlberg, J. and Johnson, A. 2001. Nuclear Export of the Large
Ribosomal Subunit, Cold Spring Harbor Symposia on Quantitative Biology
LXVI: The Ribosome, 599-605.
Trotta, C.R., Lund, E.,, Kahan, L., Johnson, A., and Dahlberg, J. 2003.
Coordinated Nuclear Export of 60S Ribosomal Subunits and NMD3 in
Vertebrates. EMBO Journal 22: 2841-2851.
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University
of Wisconsin - Department
of Biomolecular Chemistry
First published: 01/01/05 Last updated:
1/18/05 Email Biomolecular Chemistry
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